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Anne of Ostfriesland (June 26, 1562 – April 21, 1621) was the eldest daughter of Count Edzard II of East Frisia and his wife, Catherine Vasa, daughter of Gustav I of Sweden.

Anne married three times:

• First, on July 12, 1583, in Heidelberg, to the Elector Palatine, Louis VI. He died on October 22 of the same year.
• Second, Anne remarried on December 21, 1585, Ernest Frederick, Margrave of Baden-Durlach. He died April 14, 1604.
• Third, Anne married on March 7, 1617, in Grabow, Julius Henry, later Duke of Saxe-Lauenburg. The duke was 26 years younger than his wife and outlived her by many decades, dying on November 20, 1665.

Anne had no living children by any of her husbands. She was buried in the Church of the Holy Spirit, Heidelberg, but her grave is not preserved.

Louis VI du Palatinat (4 juillet 1539, Simmern – 22 octobre 1583, Heidelberg), électeur palatin de la branche Palatinat-Simmern de la Maison de Wittelsbach, convertit le Palatinat au luthéranisme. Il réforme l’Université de Heidelberg et modernise l’administration du pays.

Julius Henry (9 April 1586 – 20 November 1665) was duke of Saxe-Lauenburg between 1656 and 1665. Before ascending to the throne he served as Field Marshal in the imperial army.

Ernest Frederick of Baden-Durlach (born 17 October 1560 in Durlach – died 14 April 1604 in Remchingen) ruled the northern part of the Margraviate of Baden-Durlach. He came to power when he came of age in 1584. He founded the first Gymnasium Illustre in the margraviate. Ernst Friedrich, who had a strict Lutheran upbringing, started a reconciliation between Lutheranism and Calvinism with the publication of the Staffort Book in 1599 His occupation of Upper Baden caused serious conflicts – even with the Emperor – the consequences of which damaged Lower Baden and ultimately also led to losses of territory.